Ruthenium in PDB 8rnw: Hen Egg White Lysozyme Soaked with Trans-Ru(Dmso)4CL2

All present enzymatic activity of Hen Egg White Lysozyme Soaked with Trans-Ru(Dmso)4CL2:
3.2.1.17;

The structure of Hen Egg White Lysozyme Soaked with Trans-Ru(Dmso)4CL2, PDB code: 8rnw was solved by M.Oszajca, M.Flejszar, A.Szura, P.Drozdz, M.Brindell, K.Kurpiewska, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	18.97 / 1.12
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	78.207, 78.207, 37.195, 90, 90, 90
R / Rfree (%)	15.6 / 17.1

The structure of Hen Egg White Lysozyme Soaked with Trans-Ru(Dmso)4CL2 also contains other interesting chemical elements:

Sodium	(Na)	1 atom
Chlorine	(Cl)	4 atoms

The binding sites of Ruthenium atom in the Hen Egg White Lysozyme Soaked with Trans-Ru(Dmso)4CL2 (pdb code 8rnw). This binding sites where shown within 5.0 Angstroms radius around Ruthenium atom.
In total 2 binding sites of Ruthenium where determined in the Hen Egg White Lysozyme Soaked with Trans-Ru(Dmso)4CL2, PDB code: 8rnw:
Jump to Ruthenium binding site number: 1; 2;

Ruthenium binding site 1 out of 2 in the Hen Egg White Lysozyme Soaked with Trans-Ru(Dmso)4CL2


Mono view


Stereo pair view

A full contact list of Ruthenium with other atoms in the Ru binding site number 1 of Hen Egg White Lysozyme Soaked with Trans-Ru(Dmso)4CL2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ru202 b:39.1 occ:0.57 O A:HOH383 2.1 51.2 1.0 NH2 A:ARG14 2.3 43.4 1.0 NH1 A:ARG14 2.3 44.8 1.0 CE1 A:HIS15 2.4 32.5 0.6 NE2 A:HIS15 2.5 32.5 0.4 CZ A:ARG14 2.6 43.3 1.0 O A:HOH305 2.9 44.6 1.0 NE2 A:HIS15 3.0 32.8 0.6 CE1 A:HIS15 3.0 32.4 0.4 O A:HOH416 3.0 31.7 1.0 ND1 A:HIS15 3.5 31.6 0.6 CD2 A:HIS15 3.7 31.6 0.4 NE A:ARG14 3.9 41.1 1.0 ND1 A:HIS15 4.2 31.6 0.4 OD1 A:ASP87 4.2 33.5 1.0 CD2 A:HIS15 4.3 31.1 0.6 OG1 A:THR89 4.5 26.3 1.0 CG A:HIS15 4.5 30.6 0.4 CG A:HIS15 4.6 30.2 0.6 O A:HOH427 4.6 38.1 1.0 O A:HOH331 4.7 50.3 1.0 CG A:ASP87 4.9 32.9 1.0 CD A:ARG14 4.9 36.8 1.0

Ruthenium binding site 2 out of 2 in the Hen Egg White Lysozyme Soaked with Trans-Ru(Dmso)4CL2


Mono view


Stereo pair view

A full contact list of Ruthenium with other atoms in the Ru binding site number 2 of Hen Egg White Lysozyme Soaked with Trans-Ru(Dmso)4CL2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ru203 b:65.0 occ:0.92 OD2 A:ASP101 2.3 40.4 1.0 O A:HOH361 2.3 81.3 1.0 O A:HOH304 2.5 63.7 1.0 O A:HOH387 2.7 79.2 1.0 O A:HOH421 2.7 60.8 1.0 OD1 A:ASP101 2.9 41.0 1.0 CG A:ASP101 2.9 38.5 1.0 O A:HOH418 4.3 61.8 1.0 O A:ASP101 4.4 29.5 1.0 CB A:ASP101 4.4 31.7 1.0

M.Oszajca, M.Flejszar, A.Szura, P.Drozdz, M.Brindell, K.Kurpiewska. Exploring the Coordination Chemistry of Ruthenium Complexes with Lysozymes: Structural and in Solution Studies To Be Published.