Ruthenium in PDB 8ffm: Wildtype Rat TRPV2 in Nanodiscs Bound to Rr and 2-Apb

The binding sites of Ruthenium atom in the Wildtype Rat TRPV2 in Nanodiscs Bound to Rr and 2-Apb (pdb code 8ffm). This binding sites where shown within 5.0 Angstroms radius around Ruthenium atom.
In total 3 binding sites of Ruthenium where determined in the Wildtype Rat TRPV2 in Nanodiscs Bound to Rr and 2-Apb, PDB code: 8ffm:
Jump to Ruthenium binding site number: 1; 2; 3;

Ruthenium binding site 1 out of 3 in the Wildtype Rat TRPV2 in Nanodiscs Bound to Rr and 2-Apb


Mono view


Stereo pair view

A full contact list of Ruthenium with other atoms in the Ru binding site number 1 of Wildtype Rat TRPV2 in Nanodiscs Bound to Rr and 2-Apb within 5.0Å range: probe atom residue distance (Å) B Occ A:Ru803 b:132.6 occ:1.00 RU2 A:R2R803 0.0 132.6 1.0 O13 A:R2R803 1.8 143.8 1.0 O06 A:R2R803 1.8 142.8 1.0 N05 A:R2R803 2.0 136.4 1.0 N01 A:R2R803 2.0 136.6 1.0 N04 A:R2R803 2.0 136.7 1.0 N03 A:R2R803 2.0 136.4 1.0 RU1 A:R2R803 3.7 177.9 1.0 RU3 A:R2R803 3.7 143.8 1.0 N18 A:R2R803 4.2 140.7 1.0 N17 A:R2R803 4.2 140.8 1.0 N10 A:R2R803 4.2 139.1 1.0 N16 A:R2R803 4.2 140.7 1.0 N19 A:R2R803 4.2 140.9 1.0 N09 A:R2R803 4.2 138.9 1.0 N11 A:R2R803 4.2 139.0 1.0 N12 A:R2R803 4.2 139.0 1.0 O C:GLY606 4.4 80.7 1.0 O D:GLY606 4.5 79.2 1.0 O B:GLY606 4.5 79.9 1.0 O A:GLY606 4.5 79.0 1.0

Ruthenium binding site 2 out of 3 in the Wildtype Rat TRPV2 in Nanodiscs Bound to Rr and 2-Apb


Mono view


Stereo pair view

A full contact list of Ruthenium with other atoms in the Ru binding site number 2 of Wildtype Rat TRPV2 in Nanodiscs Bound to Rr and 2-Apb within 5.0Å range: probe atom residue distance (Å) B Occ A:Ru803 b:143.8 occ:1.00 RU3 A:R2R803 0.0 143.8 1.0 O06 A:R2R803 1.8 142.8 1.0 N08 A:R2R803 2.0 141.3 1.0 N10 A:R2R803 2.0 139.1 1.0 N09 A:R2R803 2.0 138.9 1.0 N12 A:R2R803 2.0 139.0 1.0 N11 A:R2R803 2.0 139.0 1.0 RU2 A:R2R803 3.7 132.6 1.0 O C:GLY606 4.1 80.7 1.0 O D:GLY606 4.1 79.2 1.0 O B:GLY606 4.1 79.9 1.0 O A:GLY606 4.1 79.0 1.0 N03 A:R2R803 4.2 136.4 1.0 N05 A:R2R803 4.2 136.4 1.0 N01 A:R2R803 4.2 136.6 1.0 N04 A:R2R803 4.2 136.7 1.0

Ruthenium binding site 3 out of 3 in the Wildtype Rat TRPV2 in Nanodiscs Bound to Rr and 2-Apb


Mono view


Stereo pair view

A full contact list of Ruthenium with other atoms in the Ru binding site number 3 of Wildtype Rat TRPV2 in Nanodiscs Bound to Rr and 2-Apb within 5.0Å range: probe atom residue distance (Å) B Occ A:Ru803 b:177.9 occ:1.00 RU1 A:R2R803 0.0 177.9 1.0 O13 A:R2R803 1.8 143.8 1.0 N17 A:R2R803 2.0 140.8 1.0 N18 A:R2R803 2.0 140.7 1.0 N19 A:R2R803 2.0 140.9 1.0 N16 A:R2R803 2.0 140.7 1.0 N15 A:R2R803 2.0 142.8 1.0 RU2 A:R2R803 3.7 132.6 1.0 N04 A:R2R803 4.2 136.7 1.0 N01 A:R2R803 4.2 136.6 1.0 N05 A:R2R803 4.2 136.4 1.0 N03 A:R2R803 4.2 136.4 1.0

R.A.Pumroy, J.J.De Jesus-Perez, A.D.Protopopova, J.A.Rocereta, E.C.Fluck, T.Fricke, B.H.Lee, T.Rohacs, A.Leffler, V.Moiseenkova-Bell. Molecular Details of Ruthenium Red Pore Block in Trpv Channels. Embo Rep. 2024.
ISSN: ESSN 1469-3178
PubMed: 38225355
DOI: 10.1038/S44319-023-00050-0