Ruthenium in PDB 6uiw: Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State
Ruthenium Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
20;
Page 3, Binding sites: 21 -
30;
Page 4, Binding sites: 31 -
33;
Binding sites:
The binding sites of Ruthenium atom in the Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State
(pdb code 6uiw). This binding sites where shown within
5.0 Angstroms radius around Ruthenium atom.
In total 33 binding sites of Ruthenium where determined in the
Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State, PDB code: 6uiw:
Jump to Ruthenium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Ruthenium binding site 1 out
of 33 in 6uiw
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Ruthenium Binding Sites List in 6uiw
Ruthenium binding site 1 out
of 33 in the Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State
Mono view
Stereo pair view
|
A full contact list of Ruthenium with other atoms in the Ru binding
site number 1 of Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ru501
b:20.0
occ:1.00
|
RU2
|
A:R2R501
|
0.0
|
20.0
|
1.0
|
O13
|
A:R2R501
|
1.8
|
20.0
|
1.0
|
O06
|
A:R2R501
|
1.8
|
20.0
|
1.0
|
N01
|
A:R2R501
|
2.0
|
20.0
|
1.0
|
N05
|
A:R2R501
|
2.0
|
20.0
|
1.0
|
N03
|
A:R2R501
|
2.0
|
20.0
|
1.0
|
N04
|
A:R2R501
|
2.0
|
20.0
|
1.0
|
RU1
|
A:R2R501
|
3.7
|
20.0
|
1.0
|
RU3
|
A:R2R501
|
3.7
|
20.0
|
1.0
|
N16
|
A:R2R501
|
4.2
|
20.0
|
1.0
|
N11
|
A:R2R501
|
4.2
|
20.0
|
1.0
|
N19
|
A:R2R501
|
4.2
|
20.0
|
1.0
|
N17
|
A:R2R501
|
4.2
|
20.0
|
1.0
|
N18
|
A:R2R501
|
4.2
|
20.0
|
1.0
|
N12
|
A:R2R501
|
4.2
|
20.0
|
1.0
|
N09
|
A:R2R501
|
4.2
|
20.0
|
1.0
|
N10
|
A:R2R501
|
4.2
|
20.0
|
1.0
|
NH1
|
A:ARG124
|
4.5
|
0.7
|
1.0
|
CZ
|
A:ARG124
|
4.9
|
0.7
|
1.0
|
|
Ruthenium binding site 2 out
of 33 in 6uiw
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Ruthenium Binding Sites List in 6uiw
Ruthenium binding site 2 out
of 33 in the Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State
Mono view
Stereo pair view
|
A full contact list of Ruthenium with other atoms in the Ru binding
site number 2 of Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ru501
b:20.0
occ:1.00
|
RU3
|
A:R2R501
|
0.0
|
20.0
|
1.0
|
O06
|
A:R2R501
|
1.8
|
20.0
|
1.0
|
N09
|
A:R2R501
|
2.0
|
20.0
|
1.0
|
N10
|
A:R2R501
|
2.0
|
20.0
|
1.0
|
N12
|
A:R2R501
|
2.0
|
20.0
|
1.0
|
N11
|
A:R2R501
|
2.0
|
20.0
|
1.0
|
N08
|
A:R2R501
|
2.0
|
20.0
|
1.0
|
RU2
|
A:R2R501
|
3.7
|
20.0
|
1.0
|
NH2
|
A:ARG124
|
4.0
|
0.7
|
1.0
|
N03
|
A:R2R501
|
4.2
|
20.0
|
1.0
|
N01
|
A:R2R501
|
4.2
|
20.0
|
1.0
|
N05
|
A:R2R501
|
4.2
|
20.0
|
1.0
|
N04
|
A:R2R501
|
4.2
|
20.0
|
1.0
|
CB
|
A:PHE39
|
4.3
|
0.3
|
1.0
|
O
|
A:PHE39
|
4.6
|
0.3
|
1.0
|
CZ
|
A:ARG124
|
4.8
|
0.7
|
1.0
|
NH1
|
A:ARG124
|
4.9
|
0.7
|
1.0
|
|
Ruthenium binding site 3 out
of 33 in 6uiw
Go back to
Ruthenium Binding Sites List in 6uiw
Ruthenium binding site 3 out
of 33 in the Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State
Mono view
Stereo pair view
|
A full contact list of Ruthenium with other atoms in the Ru binding
site number 3 of Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ru501
b:20.0
occ:1.00
|
RU1
|
A:R2R501
|
0.0
|
20.0
|
1.0
|
O13
|
A:R2R501
|
1.8
|
20.0
|
1.0
|
N18
|
A:R2R501
|
2.0
|
20.0
|
1.0
|
N17
|
A:R2R501
|
2.0
|
20.0
|
1.0
|
N19
|
A:R2R501
|
2.0
|
20.0
|
1.0
|
N16
|
A:R2R501
|
2.0
|
20.0
|
1.0
|
N15
|
A:R2R501
|
2.0
|
20.0
|
1.0
|
RU2
|
A:R2R501
|
3.7
|
20.0
|
1.0
|
N04
|
A:R2R501
|
4.2
|
20.0
|
1.0
|
N01
|
A:R2R501
|
4.2
|
20.0
|
1.0
|
N05
|
A:R2R501
|
4.2
|
20.0
|
1.0
|
N03
|
A:R2R501
|
4.2
|
20.0
|
1.0
|
CD1
|
A:ILE120
|
4.7
|
87.5
|
1.0
|
CG2
|
A:ILE120
|
4.8
|
87.5
|
1.0
|
CZ3
|
A:TRP117
|
4.8
|
83.1
|
1.0
|
|
Ruthenium binding site 4 out
of 33 in 6uiw
Go back to
Ruthenium Binding Sites List in 6uiw
Ruthenium binding site 4 out
of 33 in the Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State
Mono view
Stereo pair view
|
A full contact list of Ruthenium with other atoms in the Ru binding
site number 4 of Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ru501
b:20.0
occ:1.00
|
RU2
|
B:R2R501
|
0.0
|
20.0
|
1.0
|
O13
|
B:R2R501
|
1.8
|
20.0
|
1.0
|
O06
|
B:R2R501
|
1.8
|
20.0
|
1.0
|
N01
|
B:R2R501
|
2.0
|
20.0
|
1.0
|
N03
|
B:R2R501
|
2.0
|
20.0
|
1.0
|
N05
|
B:R2R501
|
2.0
|
20.0
|
1.0
|
N04
|
B:R2R501
|
2.0
|
20.0
|
1.0
|
RU1
|
B:R2R501
|
3.7
|
20.0
|
1.0
|
RU3
|
B:R2R501
|
3.7
|
20.0
|
1.0
|
N19
|
B:R2R501
|
4.2
|
20.0
|
1.0
|
N17
|
B:R2R501
|
4.2
|
20.0
|
1.0
|
N16
|
B:R2R501
|
4.2
|
20.0
|
1.0
|
N18
|
B:R2R501
|
4.2
|
20.0
|
1.0
|
N11
|
B:R2R501
|
4.2
|
20.0
|
1.0
|
N12
|
B:R2R501
|
4.2
|
20.0
|
1.0
|
N09
|
B:R2R501
|
4.2
|
20.0
|
1.0
|
N10
|
B:R2R501
|
4.2
|
20.0
|
1.0
|
NH1
|
B:ARG124
|
4.5
|
0.7
|
1.0
|
CZ
|
B:ARG124
|
4.9
|
0.7
|
1.0
|
|
Ruthenium binding site 5 out
of 33 in 6uiw
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Ruthenium Binding Sites List in 6uiw
Ruthenium binding site 5 out
of 33 in the Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State
Mono view
Stereo pair view
|
A full contact list of Ruthenium with other atoms in the Ru binding
site number 5 of Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ru501
b:20.0
occ:1.00
|
RU3
|
B:R2R501
|
0.0
|
20.0
|
1.0
|
O06
|
B:R2R501
|
1.8
|
20.0
|
1.0
|
N09
|
B:R2R501
|
2.0
|
20.0
|
1.0
|
N12
|
B:R2R501
|
2.0
|
20.0
|
1.0
|
N10
|
B:R2R501
|
2.0
|
20.0
|
1.0
|
N11
|
B:R2R501
|
2.0
|
20.0
|
1.0
|
N08
|
B:R2R501
|
2.0
|
20.0
|
1.0
|
RU2
|
B:R2R501
|
3.7
|
20.0
|
1.0
|
NH2
|
B:ARG124
|
4.0
|
0.7
|
1.0
|
N03
|
B:R2R501
|
4.2
|
20.0
|
1.0
|
N01
|
B:R2R501
|
4.2
|
20.0
|
1.0
|
N05
|
B:R2R501
|
4.2
|
20.0
|
1.0
|
N04
|
B:R2R501
|
4.2
|
20.0
|
1.0
|
CB
|
B:PHE39
|
4.3
|
0.3
|
1.0
|
O
|
B:PHE39
|
4.6
|
0.3
|
1.0
|
CZ
|
B:ARG124
|
4.8
|
0.7
|
1.0
|
NH1
|
B:ARG124
|
4.9
|
0.7
|
1.0
|
|
Ruthenium binding site 6 out
of 33 in 6uiw
Go back to
Ruthenium Binding Sites List in 6uiw
Ruthenium binding site 6 out
of 33 in the Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State
Mono view
Stereo pair view
|
A full contact list of Ruthenium with other atoms in the Ru binding
site number 6 of Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ru501
b:20.0
occ:1.00
|
RU1
|
B:R2R501
|
0.0
|
20.0
|
1.0
|
O13
|
B:R2R501
|
1.8
|
20.0
|
1.0
|
N18
|
B:R2R501
|
2.0
|
20.0
|
1.0
|
N17
|
B:R2R501
|
2.0
|
20.0
|
1.0
|
N19
|
B:R2R501
|
2.0
|
20.0
|
1.0
|
N16
|
B:R2R501
|
2.0
|
20.0
|
1.0
|
N15
|
B:R2R501
|
2.0
|
20.0
|
1.0
|
RU2
|
B:R2R501
|
3.7
|
20.0
|
1.0
|
N04
|
B:R2R501
|
4.2
|
20.0
|
1.0
|
N01
|
B:R2R501
|
4.2
|
20.0
|
1.0
|
N03
|
B:R2R501
|
4.2
|
20.0
|
1.0
|
N05
|
B:R2R501
|
4.2
|
20.0
|
1.0
|
CD1
|
B:ILE120
|
4.7
|
87.5
|
1.0
|
CG2
|
B:ILE120
|
4.8
|
87.5
|
1.0
|
CZ3
|
B:TRP117
|
4.8
|
83.1
|
1.0
|
|
Ruthenium binding site 7 out
of 33 in 6uiw
Go back to
Ruthenium Binding Sites List in 6uiw
Ruthenium binding site 7 out
of 33 in the Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State
Mono view
Stereo pair view
|
A full contact list of Ruthenium with other atoms in the Ru binding
site number 7 of Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ru501
b:20.0
occ:1.00
|
RU2
|
C:R2R501
|
0.0
|
20.0
|
1.0
|
O13
|
C:R2R501
|
1.8
|
20.0
|
1.0
|
O06
|
C:R2R501
|
1.8
|
20.0
|
1.0
|
N01
|
C:R2R501
|
2.0
|
20.0
|
1.0
|
N05
|
C:R2R501
|
2.0
|
20.0
|
1.0
|
N03
|
C:R2R501
|
2.0
|
20.0
|
1.0
|
N04
|
C:R2R501
|
2.0
|
20.0
|
1.0
|
RU1
|
C:R2R501
|
3.7
|
20.0
|
1.0
|
RU3
|
C:R2R501
|
3.7
|
20.0
|
1.0
|
N16
|
C:R2R501
|
4.2
|
20.0
|
1.0
|
N19
|
C:R2R501
|
4.2
|
20.0
|
1.0
|
N11
|
C:R2R501
|
4.2
|
20.0
|
1.0
|
N18
|
C:R2R501
|
4.2
|
20.0
|
1.0
|
N17
|
C:R2R501
|
4.2
|
20.0
|
1.0
|
N10
|
C:R2R501
|
4.2
|
20.0
|
1.0
|
N09
|
C:R2R501
|
4.2
|
20.0
|
1.0
|
N12
|
C:R2R501
|
4.2
|
20.0
|
1.0
|
NH1
|
C:ARG124
|
4.5
|
0.7
|
1.0
|
CZ
|
C:ARG124
|
4.9
|
0.7
|
1.0
|
|
Ruthenium binding site 8 out
of 33 in 6uiw
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Ruthenium Binding Sites List in 6uiw
Ruthenium binding site 8 out
of 33 in the Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State
Mono view
Stereo pair view
|
A full contact list of Ruthenium with other atoms in the Ru binding
site number 8 of Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ru501
b:20.0
occ:1.00
|
RU3
|
C:R2R501
|
0.0
|
20.0
|
1.0
|
O06
|
C:R2R501
|
1.8
|
20.0
|
1.0
|
N10
|
C:R2R501
|
2.0
|
20.0
|
1.0
|
N09
|
C:R2R501
|
2.0
|
20.0
|
1.0
|
N12
|
C:R2R501
|
2.0
|
20.0
|
1.0
|
N11
|
C:R2R501
|
2.0
|
20.0
|
1.0
|
N08
|
C:R2R501
|
2.0
|
20.0
|
1.0
|
RU2
|
C:R2R501
|
3.7
|
20.0
|
1.0
|
NH2
|
C:ARG124
|
4.0
|
0.7
|
1.0
|
N03
|
C:R2R501
|
4.2
|
20.0
|
1.0
|
N05
|
C:R2R501
|
4.2
|
20.0
|
1.0
|
N01
|
C:R2R501
|
4.2
|
20.0
|
1.0
|
N04
|
C:R2R501
|
4.2
|
20.0
|
1.0
|
CB
|
C:PHE39
|
4.3
|
0.3
|
1.0
|
O
|
C:PHE39
|
4.6
|
0.3
|
1.0
|
CZ
|
C:ARG124
|
4.8
|
0.7
|
1.0
|
NH1
|
C:ARG124
|
4.9
|
0.7
|
1.0
|
|
Ruthenium binding site 9 out
of 33 in 6uiw
Go back to
Ruthenium Binding Sites List in 6uiw
Ruthenium binding site 9 out
of 33 in the Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State
Mono view
Stereo pair view
|
A full contact list of Ruthenium with other atoms in the Ru binding
site number 9 of Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ru501
b:20.0
occ:1.00
|
RU1
|
C:R2R501
|
0.0
|
20.0
|
1.0
|
O13
|
C:R2R501
|
1.8
|
20.0
|
1.0
|
N17
|
C:R2R501
|
2.0
|
20.0
|
1.0
|
N19
|
C:R2R501
|
2.0
|
20.0
|
1.0
|
N18
|
C:R2R501
|
2.0
|
20.0
|
1.0
|
N15
|
C:R2R501
|
2.0
|
20.0
|
1.0
|
N16
|
C:R2R501
|
2.0
|
20.0
|
1.0
|
RU2
|
C:R2R501
|
3.7
|
20.0
|
1.0
|
N04
|
C:R2R501
|
4.2
|
20.0
|
1.0
|
N01
|
C:R2R501
|
4.2
|
20.0
|
1.0
|
N03
|
C:R2R501
|
4.2
|
20.0
|
1.0
|
N05
|
C:R2R501
|
4.2
|
20.0
|
1.0
|
CD1
|
C:ILE120
|
4.7
|
87.5
|
1.0
|
CG2
|
C:ILE120
|
4.8
|
87.5
|
1.0
|
CZ3
|
C:TRP117
|
4.8
|
83.1
|
1.0
|
|
Ruthenium binding site 10 out
of 33 in 6uiw
Go back to
Ruthenium Binding Sites List in 6uiw
Ruthenium binding site 10 out
of 33 in the Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State
Mono view
Stereo pair view
|
A full contact list of Ruthenium with other atoms in the Ru binding
site number 10 of Cryo-Em Structure of Human CALHM2 in A Ruthenium Red-Bound Inhibited State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ru501
b:20.0
occ:1.00
|
RU2
|
D:R2R501
|
0.0
|
20.0
|
1.0
|
O13
|
D:R2R501
|
1.8
|
20.0
|
1.0
|
O06
|
D:R2R501
|
1.8
|
20.0
|
1.0
|
N01
|
D:R2R501
|
2.0
|
20.0
|
1.0
|
N05
|
D:R2R501
|
2.0
|
20.0
|
1.0
|
N03
|
D:R2R501
|
2.0
|
20.0
|
1.0
|
N04
|
D:R2R501
|
2.0
|
20.0
|
1.0
|
RU3
|
D:R2R501
|
3.7
|
20.0
|
1.0
|
RU1
|
D:R2R501
|
3.7
|
20.0
|
1.0
|
N11
|
D:R2R501
|
4.2
|
20.0
|
1.0
|
N16
|
D:R2R501
|
4.2
|
20.0
|
1.0
|
N09
|
D:R2R501
|
4.2
|
20.0
|
1.0
|
N10
|
D:R2R501
|
4.2
|
20.0
|
1.0
|
N17
|
D:R2R501
|
4.2
|
20.0
|
1.0
|
N18
|
D:R2R501
|
4.2
|
20.0
|
1.0
|
N12
|
D:R2R501
|
4.2
|
20.0
|
1.0
|
N19
|
D:R2R501
|
4.2
|
20.0
|
1.0
|
NH1
|
D:ARG124
|
4.5
|
0.7
|
1.0
|
CZ
|
D:ARG124
|
4.9
|
0.7
|
1.0
|
|
Reference:
W.Choi,
N.Clemente,
W.Sun,
J.Du,
W.Lu.
The Structures and Gating Mechanism of Human Calcium Homeostasis Modulator 2 Nature 2019.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-019-1781-3
Page generated: Thu Oct 10 13:07:55 2024
|