Ruthenium in PDB 5lvg: Hen Egg White Lysozyme Soaked with Cis-Ru(Dmso)4CL2

All present enzymatic activity of Hen Egg White Lysozyme Soaked with Cis-Ru(Dmso)4CL2:
3.2.1.17;

The structure of Hen Egg White Lysozyme Soaked with Cis-Ru(Dmso)4CL2, PDB code: 5lvg was solved by K.Kurpiewska, P.Halajko, K.Lewinski, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	14.42 / 2.00
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	78.199, 78.199, 37.189, 90.00, 90.00, 90.00
R / Rfree (%)	15.8 / 23.3

The structure of Hen Egg White Lysozyme Soaked with Cis-Ru(Dmso)4CL2 also contains other interesting chemical elements:

Chlorine	(Cl)	4 atoms
Sodium	(Na)	1 atom

The binding sites of Ruthenium atom in the Hen Egg White Lysozyme Soaked with Cis-Ru(Dmso)4CL2 (pdb code 5lvg). This binding sites where shown within 5.0 Angstroms radius around Ruthenium atom.
In total only one binding site of Ruthenium was determined in the Hen Egg White Lysozyme Soaked with Cis-Ru(Dmso)4CL2, PDB code: 5lvg:

Ruthenium binding site 1 out of 1 in the Hen Egg White Lysozyme Soaked with Cis-Ru(Dmso)4CL2


Mono view


Stereo pair view

A full contact list of Ruthenium with other atoms in the Ru binding site number 1 of Hen Egg White Lysozyme Soaked with Cis-Ru(Dmso)4CL2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ru201 b:24.5 occ:0.80 NH2 A:ARG14 2.0 21.2 0.8 O A:HOH330 2.1 31.6 0.8 NE2 A:HIS15 2.4 22.3 1.0 O A:HOH301 2.5 17.7 0.8 CL A:CL204 2.8 28.9 0.8 NH1 A:ARG14 2.9 15.2 0.2 CZ A:ARG14 3.0 21.0 0.8 CE1 A:HIS15 3.2 22.6 1.0 NH1 A:ARG14 3.2 21.8 0.8 NE A:ARG14 3.3 16.2 0.2 CD2 A:HIS15 3.4 22.6 1.0 CZ A:ARG14 3.5 15.7 0.2 NE A:ARG14 4.2 22.0 0.8 ND1 A:HIS15 4.3 22.9 1.0 CG A:HIS15 4.5 21.7 1.0 OD1 A:ASP87 4.5 20.8 1.0 CD A:ARG14 4.6 16.6 0.2 OG1 A:THR89 4.6 16.6 1.0 CD A:ARG14 4.8 21.6 0.8 NH2 A:ARG14 4.8 15.7 0.2 O A:HOH312 4.8 25.3 1.0

M.Oszajca, K.Kurpiewska, P.Halajko, A.Szura, K.Lewinski, M.Brindell. Ligand-Dependent Interaction of Anticancer Ruthenium Complexes with Hen Egg White Lysozyme and Human Lysozyme To Be Published.