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Atomistry » Ruthenium » PDB 4l55-5ira » 4rlp » |
Ruthenium in PDB 4rlp: Human P70S6K1 with Ruthenium-Based Inhibitor FL772Enzymatic activity of Human P70S6K1 with Ruthenium-Based Inhibitor FL772
All present enzymatic activity of Human P70S6K1 with Ruthenium-Based Inhibitor FL772:
2.7.11.1; Protein crystallography data
The structure of Human P70S6K1 with Ruthenium-Based Inhibitor FL772, PDB code: 4rlp
was solved by
J.F.Domsic,
J.Barber-Rotenberg,
J.Salami,
J.Qin,
R.Marmorstein,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4rlp:
The structure of Human P70S6K1 with Ruthenium-Based Inhibitor FL772 also contains other interesting chemical elements:
Ruthenium Binding Sites:
The binding sites of Ruthenium atom in the Human P70S6K1 with Ruthenium-Based Inhibitor FL772
(pdb code 4rlp). This binding sites where shown within
5.0 Angstroms radius around Ruthenium atom.
In total only one binding site of Ruthenium was determined in the Human P70S6K1 with Ruthenium-Based Inhibitor FL772, PDB code: 4rlp: Ruthenium binding site 1 out of 1 in 4rlpGo back to![]() ![]()
Ruthenium binding site 1 out
of 1 in the Human P70S6K1 with Ruthenium-Based Inhibitor FL772
![]() Mono view ![]() Stereo pair view
Reference:
J.Qin,
R.Rajaratnam,
L.Feng,
J.Salami,
J.S.Barber-Rotenberg,
J.Domsic,
P.Reyes-Uribe,
H.Liu,
W.Dang,
S.L.Berger,
J.Villanueva,
E.Meggers,
R.Marmorstein.
Development of Organometallic S6K1 Inhibitors. J.Med.Chem. V. 58 305 2015.
Page generated: Wed Dec 16 02:08:22 2020
ISSN: ISSN 0022-2623 PubMed: 25356520 DOI: 10.1021/JM5011868 |
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