Atomistry » Ruthenium » PDB 1bex-3fy0 » 3fxz
Atomistry »
  Ruthenium »
    PDB 1bex-3fy0 »
      3fxz »

Ruthenium in PDB 3fxz: Crystal Structure of PAK1 Kinase Domain with Ruthenium Complex Lambda-FL172

Enzymatic activity of Crystal Structure of PAK1 Kinase Domain with Ruthenium Complex Lambda-FL172

All present enzymatic activity of Crystal Structure of PAK1 Kinase Domain with Ruthenium Complex Lambda-FL172:
2.7.11.1;

Protein crystallography data

The structure of Crystal Structure of PAK1 Kinase Domain with Ruthenium Complex Lambda-FL172, PDB code: 3fxz was solved by J.Maksimoska, R.Marmorstein, E.Meggers, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 26.38 / 1.64
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 52.183, 103.475, 122.653, 90.00, 90.00, 90.00
R / Rfree (%) 19.5 / 21.8

Other elements in 3fxz:

The structure of Crystal Structure of PAK1 Kinase Domain with Ruthenium Complex Lambda-FL172 also contains other interesting chemical elements:

Fluorine (F) 1 atom
Chlorine (Cl) 1 atom

Ruthenium Binding Sites:

The binding sites of Ruthenium atom in the Crystal Structure of PAK1 Kinase Domain with Ruthenium Complex Lambda-FL172 (pdb code 3fxz). This binding sites where shown within 5.0 Angstroms radius around Ruthenium atom.
In total only one binding site of Ruthenium was determined in the Crystal Structure of PAK1 Kinase Domain with Ruthenium Complex Lambda-FL172, PDB code: 3fxz:

Ruthenium binding site 1 out of 1 in 3fxz

Go back to Ruthenium Binding Sites List in 3fxz
Ruthenium binding site 1 out of 1 in the Crystal Structure of PAK1 Kinase Domain with Ruthenium Complex Lambda-FL172


Mono view


Stereo pair view

A full contact list of Ruthenium with other atoms in the Ru binding site number 1 of Crystal Structure of PAK1 Kinase Domain with Ruthenium Complex Lambda-FL172 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ru1

b:26.0
occ:1.00
RU20 A:FLL1 0.0 26.0 1.0
C13 A:FLL1 1.8 28.9 1.0
N15 A:FLL1 2.0 27.6 1.0
N23 A:FLL1 2.1 25.8 1.0
N21 A:FLL1 2.1 25.2 1.0
N16 A:FLL1 2.1 25.9 1.0
CL17 A:FLL1 2.4 29.3 1.0
C24 A:FLL1 2.8 24.6 1.0
C40 A:FLL1 2.9 24.9 1.0
C7 A:FLL1 2.9 30.2 1.0
C8 A:FLL1 3.0 25.9 1.0
O14 A:FLL1 3.0 28.7 1.0
C18 A:FLL1 3.1 33.3 1.0
C39 A:FLL1 3.1 24.3 1.0
C11 A:FLL1 3.1 26.7 1.0
C25 A:FLL1 3.3 25.5 1.0
C5 A:FLL1 3.7 38.2 1.0
C26 A:FLL1 4.0 24.2 1.0
C19 A:FLL1 4.0 36.5 1.0
C31 A:FLL1 4.2 24.3 1.0
C36 A:FLL1 4.3 24.9 1.0
C9 A:FLL1 4.3 28.2 1.0
C38 A:FLL1 4.4 24.8 1.0
C30 A:FLL1 4.4 24.4 1.0
C12 A:FLL1 4.4 28.3 1.0
O A:HOH57 4.6 40.6 1.0
C10 A:FLL1 4.9 26.9 1.0
C37 A:FLL1 4.9 24.9 1.0
CD1 A:ILE276 5.0 25.4 1.0

Reference:

J.Maksimoska, L.Feng, K.Harms, C.Yi, J.Kissil, R.Marmorstein, E.Meggers. Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes J.Am.Chem.Soc. V. 130 15764 2008.
ISSN: ISSN 0002-7863
PubMed: 18973295
Page generated: Wed Dec 16 02:08:01 2020

Last articles

Zn in 7RRP
Zn in 7OKY
Zn in 7OL0
Zn in 7OKX
Zn in 7ONB
Zn in 7RSF
Zn in 7OUF
Zn in 7OUG
Zn in 7OUH
Zn in 7RGN
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy