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Atomistry » Ruthenium » PDB 1bex-3fy0 » 3cst » |
Ruthenium in PDB 3cst: Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor E5E2Enzymatic activity of Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor E5E2
All present enzymatic activity of Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor E5E2:
2.7.1.153; Protein crystallography data
The structure of Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor E5E2, PDB code: 3cst
was solved by
P.Xie,
R.Marmorstein,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3cst:
The structure of Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor E5E2 also contains other interesting chemical elements:
Ruthenium Binding Sites:
The binding sites of Ruthenium atom in the Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor E5E2
(pdb code 3cst). This binding sites where shown within
5.0 Angstroms radius around Ruthenium atom.
In total only one binding site of Ruthenium was determined in the Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor E5E2, PDB code: 3cst: Ruthenium binding site 1 out of 1 in 3cstGo back to Ruthenium Binding Sites List in 3cst
Ruthenium binding site 1 out
of 1 in the Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor E5E2
Mono view Stereo pair view
Reference:
P.Xie,
D.S.Williams,
G.E.Atilla-Gokcumen,
L.Milk,
M.Xiao,
K.S.Smalley,
M.Herlyn,
E.Meggers,
R.Marmorstein.
Structure-Based Design of An Organoruthenium Phosphatidyl-Inositol-3-Kinase Inhibitor Reveals A Switch Governing Lipid Kinase Potency and Selectivity. Acs Chem.Biol. V. 3 305 2008.
Page generated: Mon Jan 25 16:02:18 2021
ISSN: ISSN 1554-8929 PubMed: 18484710 DOI: 10.1021/CB800039Y |
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