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Atomistry » Ruthenium » PDB 1bex-3fy0 » 3csf » |
Ruthenium in PDB 3csf: Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor DW2Enzymatic activity of Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor DW2
All present enzymatic activity of Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor DW2:
2.7.1.153; Protein crystallography data
The structure of Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor DW2, PDB code: 3csf
was solved by
P.Xie,
R.Marmorstein,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Ruthenium Binding Sites:
The binding sites of Ruthenium atom in the Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor DW2
(pdb code 3csf). This binding sites where shown within
5.0 Angstroms radius around Ruthenium atom.
In total only one binding site of Ruthenium was determined in the Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor DW2, PDB code: 3csf: Ruthenium binding site 1 out of 1 in 3csfGo back to Ruthenium Binding Sites List in 3csf
Ruthenium binding site 1 out
of 1 in the Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor DW2
Mono view Stereo pair view
Reference:
P.Xie,
D.S.Williams,
G.E.Atilla-Gokcumen,
L.Milk,
M.Xiao,
K.S.Smalley,
M.Herlyn,
E.Meggers,
R.Marmorstein.
Structure-Based Design of An Organoruthenium Phosphatidyl-Inositol-3-Kinase Inhibitor Reveals A Switch Governing Lipid Kinase Potency and Selectivity. Acs Chem.Biol. V. 3 305 2008.
Page generated: Wed Dec 16 02:08:00 2020
ISSN: ISSN 1554-8929 PubMed: 18484710 DOI: 10.1021/CB800039Y |
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