Ruthenium in PDB 3csf: Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor DW2

Enzymatic activity of Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor DW2

Protein crystallography data

Ruthenium Binding Sites:

Ruthenium binding site 1 out of 1 in 3csf

Ruthenium Binding Sites List in 3csf

Ruthenium binding site 1 out of 1 in the Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor DW2


Mono view


Stereo pair view

A full contact list of Ruthenium with other atoms in the Ru binding site number 1 of Crystal Structure of PI3K P110GAMMA Catalytical Domain in Complex with Organoruthenium Inhibitor DW2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ru1 b:1.0 occ:0.92 RU18 A:DW21 0.0 1.0 0.9 N21 A:DW21 2.0 0.4 0.9 N19 A:DW21 2.0 0.8 0.9 C10 A:DW21 2.0 0.0 0.9 C12 A:DW21 2.1 0.1 0.9 C17 A:DW21 2.1 0.1 0.9 C13 A:DW21 2.1 0.3 0.9 C16 A:DW21 2.1 0.3 0.9 C14 A:DW21 2.1 0.3 0.9 C22 A:DW21 2.8 0.6 0.9 C7 A:DW21 2.8 0.3 0.9 C6 A:DW21 3.0 0.8 0.9 O11 A:DW21 3.2 0.2 0.9 C23 A:DW21 3.3 0.6 0.9 C24 A:DW21 4.0 0.5 0.9 C29 A:DW21 4.1 0.1 0.9 C3 A:DW21 4.2 0.8 0.9 C28 A:DW21 4.3 0.6 0.9 C5 A:DW21 4.3 0.5 0.9 NZ A:LYS890 4.4 0.2 1.0 CE A:LYS890 4.6 0.0 1.0 CZ3 A:TRP812 4.8 52.5 1.0 C4 A:DW21 4.8 0.8 0.9 O A:HOH1212 4.9 88.2 1.0

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